Read e-book online Angiotensin and the Heart PDF

By Gerd Heusch,H. Grobecker,B.E. Strauer

ISBN-10: 0387914323

ISBN-13: 9780387914329

ISBN-10: 3798509360

ISBN-13: 9783798509368

within the final decade, ACE inhibitors became a cornerstone of cardiovascular drug treatment. worthwhile results in sufferers with high blood pressure, center failure, and publish myocardial infarction were proven in huge scientific trials. In parallel, ex perimental examine has shifted the curiosity from the speedy homeostatic functionality of the circulating renin-angiotensin-system to the a number of paracrine capabilities of neighborhood tissue renin-angiotensin-systems, together with hypertrophy, hyperplasia, athe- oenesis, and vasomotion. . It was once the purpose or a symposium held in Hamburg, October 22-24, 1992, to compile a world panel of experimental and medical scientists and to debate the latest findings at the function of angiotensin and linked mediators in motor vehicle diovascular version and ailment, with a specific emphasis at the remedy of such sickness through ACE inhibitors. The assembly and this e-book have been generously supported through Astra chemical compounds. H. Grobecker G. Heusch B. E. Strauer Contents Foreword. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . V advent neighborhood expression and pathophysiological position of renin-angiotensin within the blood vessels and center Dzau, V. J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Myocardial Perfusion Angiotensin, ACE-inhibitors and endothelial keep watch over of vasomotor tone Luscher, T. F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 neighborhood and neurohumoral keep watch over of coronary blood circulation Krajcar, M., G. Heusch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 ACE-inhibitors in coronary artery affliction? Vogt, M., W. Matz, B. E. Strauer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . forty three Myocardial Hypertrophy Molecular mechanisms of cardiac gene expression Nadal-Ginard, B., V. Mahdavi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . sixty five Myocardial perfusion established and self sufficient mechanisms of local myocardial disorder in hypertrophy Vatner, S. F., L. Hittinger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Angiotensin and the Heart by Gerd Heusch,H. Grobecker,B.E. Strauer


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